The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2025
Filed:
Mar. 30, 2021
Uppthera, Incheon, KR;
Si Woo Choi, Incheon, KR;
Soo Hee Ryu, Incheon, KR;
Ji Hoon Ryu, Seoul, KR;
San Ha Son, Incheon, KR;
Hwa Jin Lee, Incheon, KR;
Seong Hoon Kim, Incheon, KR;
Eun Bin Lee, Incheon, KR;
Hye Guk Ryu, Incheon, KR;
Im Suk Min, Gyeonggi-do, KR;
Jun Kyu Lee, Gyeonggi-do, KR;
UPPTHERA INC., Incheon, KR;
Abstract
The present invention relates HMG-CoA reductase degradation inducing compounds. Specifically, the present invention relates a bifunctional compound in which a HMG-CoA reductase binding moiety and an E3 ubiquitin ligase-binding moiety are linked by a chemical linker. The present invention also relates a method for preparing the compounds, and a method for degradation of HMG-CoA reductase using the compounds, as well as use for prevention or treatment of HMG-CoA reductase related diseases using the compounds.