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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12479827 B1

PDFFull Text
Date of Patent:
Nov. 25, 2025

Filed:

Aug. 25, 2023

Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors

Applicant:

Boehringer Ingelheim International Gmbh, Ingelheim am Rhein, DE;

Inventors:

Matthias Eckhardt, Biberach an der Riss, DE;

Maude Giroud, Basel, CH;

Elke Langkopf, Biberach an der Riss, DE;

Camilla Mayer, Warthausen, DE;

Holger Wagner, Mettenberg, DE;

Dieter Wiedenmayer, Bieberach an der Riss, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorney:

Shelley A. Jones

Primary Examiner:

Brian E Mcdowell

Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/4439 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); A61K 31/519 (2006.01); A61K 45/06 (2006.01); C07D 235/02 (2006.01); C07D 403/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/4439 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 31/519 (2013.01); A61K 45/06 (2013.01); C07D 235/02 (2013.01); C07D 403/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 487/04 (2013.01);
Abstract

Disclosed are heteroaromatic carboxamides of formula (I), wherein Y, R, and Ar are as defined herein, and pharmaceutically acceptable salts thereof. Also disclosed are the use of the compounds of formula (i) for the treatment of diseases which can be influenced by the inhibition of plasma kallikrein.

Find Patent Forward Citations

Eckhardt, Matthias. (2025). Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors (U.S. Patent No. 12479827). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12479827

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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