The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Apr. 03, 2020
Applicant:

University of Central Florida Research Foundation, Inc., Orlando, FL (US);

Inventors:

Debopam Chakrabarti, Orlando, FL (US);

Yu Yuan, Orlando, FL (US);

Guang Huang, Orlando, FL (US);

Claribel Murillo Solano, Orlando, FL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 215/46 (2006.01); A61P 33/06 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 405/06 (2006.01); C07D 409/06 (2006.01); C07D 417/06 (2006.01);
U.S. Cl.
CPC ...
C07D 215/46 (2013.01); A61P 33/06 (2018.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 417/06 (2013.01);
Abstract

Antimalarial compounds of the formula: in which n is 1 or 2; X is C or N; Ris a moiety comprising a secondary amine and a tertiary amine joined by a Cto Calkyl chain; and Ris CF, F, or H, or an analog, combination, derivative, prodrug, stereoisomer, or pharmaceutically acceptable salt thereof. Pharmaceutical compounds including the antimalarial compounds. Methods of treating or preventing malaria comprising administering an effective amount of the antimalarial compounds.


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