The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Feb. 26, 2021
Applicants:

Paris Sciences ET Lettres—quartier Latin, Paris, FR;

Centre National DE LA Recherche Scientifique (Cnrs), Paris, FR;

Universite Paris Diderot Paris 7, Paris, FR;

Sorbonne Universite, Paris, FR;

Inventors:

Vincent Croquette, Antony, FR;

David Bensimon, Paris, FR;

Jimmy Ouellet, Lardy, FR;

Jean-François Allemand, Bourg la Reine, FR;

Charles Andre, Paris, FR;

Gordon Hamilton, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); C12Q 1/6825 (2018.01); G01N 27/07 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
B01L 3/50273 (2013.01); C12Q 1/6825 (2013.01); G01N 27/3275 (2013.01); B01L 3/5085 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0829 (2013.01); B01L 2400/043 (2013.01); B01L 2400/0436 (2013.01); C12Q 2523/307 (2013.01); C12Q 2525/301 (2013.01); C12Q 2563/116 (2013.01); C12Q 2563/155 (2013.01); G01N 27/07 (2013.01);
Abstract

The invention proposes a device for analyzing nucleic acid molecules (M), comprising: —a bead (), on which one molecule can be anchored at one end, —a surface (), on which the molecule can be anchored at the other end, —an actuator (), adapted to cause the bead to move relative to said surface in one direction, —a sensor (), adapted to measure a distance between the bead and the surface, the device further comprising a well (), having an axis (X-X) extending along the direction of motion of the bead and a bottom () formed by said surface, said well being filled with electrically conductive solution (), and receiving the bead, the sensor being adapted to measure an impedance of the well, depending on a distance between the bead and the surface, to determine, the distance between the bead and the surface.


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