The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Jan. 08, 2021
Applicant:

Beckman Coulter, Inc., Brea, CA (US);

Inventors:

John M. Wallach, Diamond Bar, CA (US);

Xihai Mu, Eastvale, CA (US);

Assignee:

Beckman Coulter, Inc., Brea, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 27/403 (2006.01); B01L 3/00 (2006.01); G01N 33/487 (2006.01); G01N 33/84 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502 (2013.01); G01N 27/4035 (2013.01); G01N 33/48707 (2013.01); G01N 33/84 (2013.01); B01L 2200/026 (2013.01); B01L 2200/0689 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0861 (2013.01);
Abstract

An ion selective electrode ('ISE') assembly may be installed within a sample path of a biological testing system to measure ion concentration within sample fluid flowing through the sample path. A transducer membrane is placed within a housing and positioned to contact the sample path. A threaded portion is advanced into a socket of the housing and forces the membrane against a sealing portion of the sample path to prevent retention of sample fluid within the housing after testing. Sealing may be accomplished without adhesives or sealants and instead relies upon mechanical pressure of the threaded portion. Another implementation includes a reference measuring electrode and several ion measuring electrodes combined into a single housing. Another implementation includes a reference measuring electrode and several ion measuring electrodes combined into a cartridge that includes a sample well instead of a sample path.


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