The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Jul. 14, 2020
Applicant:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Jean Zhao, Brookline, MA (US);

Yunneng Tang, Brookline, MA (US);

Xin Cheng, Brookline, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001134 (2018.08); A61K 39/0011 (2013.01); A61K 2039/5156 (2013.01); A61K 2039/575 (2013.01); A61K 2039/812 (2018.08);
Abstract

The present invention is based, in part, on cancer vaccine compositions that comprise PTEN- and p53-deficient cancer cells with activated TGFβ-Smad/p63 signaling pathway, and methods for using same to prevent and/or treat cancer.


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