The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Jun. 11, 2020
Applicant:

E-nitiate Biopharmaceuticals (Hangzhou) Co., Ltd, Hangzhou, CN;

Inventors:

Wang Shen, Shanghai, CN;

Pengfei Liu, Shanghai, CN;

Rujun Bai, Shanghai, CN;

Yufei Liu, Shanghai, CN;

Qiuping Luo, Shanghai, CN;

Pingbo Ke, Shanghai, CN;

Yanchuan Gong, Shanghai, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4545 (2006.01); A61K 31/438 (2006.01); A61K 31/439 (2006.01); A61K 31/496 (2006.01); A61K 31/55 (2006.01); A61K 45/06 (2006.01); C07D 471/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4545 (2013.01); A61K 31/438 (2013.01); A61K 31/439 (2013.01); A61K 31/496 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07D 471/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a cyano-substituted cyclic hydrazine derivative, comprising: a compound represented by the following structural formula or a stereoisomer, a geometric isomer, a tautomer, a racemate, a hydrate, a solvate, a metabolite and a pharmaceutically acceptable salt or a prodrug thereof. The compound is used for prevention, treatment or alleviation of autoimmune diseases or proliferative diseases in patients, and/or for inhibiting or modulating protein kinase activity.


Find Patent Forward Citations

Loading…