The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Oct. 09, 2021
Applicant:

Soochow University, Suzhou, CN;

Inventors:

Yanxia Ma, Suzhou, CN;

Shanwen Wei, Suzhou, CN;

Mingming Zou, Suzhou, CN;

Li Ni, Suzhou, CN;

Liyu Zhou, Suzhou, CN;

Di Li, Suzhou, CN;

Yanwei Yang, Suzhou, CN;

Assignee:

SOOCHOW UNIVERSITY, Suzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 31/385 (2006.01); A61K 35/30 (2015.01); A61P 25/00 (2006.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
A61K 31/385 (2013.01); A61K 35/30 (2013.01); A61P 25/00 (2018.01); C12N 5/0622 (2013.01);
Abstract

The present invention relates to use of slow-releasing hydrogen sulfide organic donor ADT-OH drugs in the differentiation of neural precursor cells. ADT-OH can induce more directed differentiation of neural precursor cells into neurons and oligodendrocytes and less differentiation into astrocytes, promote the axon growth of neurons, and reduce the death of neural precursor cells, thereby providing a direction for the transplantation of neural precursor cells to repair damaged nerves. ADT-OH will likely become a new drug target for the clinical treatment of nervous system diseases.


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