The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

Feb. 26, 2022
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Matthew Smith, Nashville, TN (US);

Gary T. Smith, Nashville, TN (US);

Jared Grice, Nashville, TN (US);

Assignee:

VANDERBILT UNIVERSITY, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 6/50 (2024.01); A61B 6/00 (2024.01); A61B 6/03 (2006.01); G06T 7/00 (2017.01); G06T 11/00 (2006.01); G06T 11/20 (2006.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01);
U.S. Cl.
CPC ...
A61B 6/507 (2013.01); A61B 6/032 (2013.01); A61B 6/482 (2013.01); A61B 6/487 (2013.01); A61B 6/504 (2013.01); G06T 7/0012 (2013.01); G06T 11/001 (2013.01); G06T 11/206 (2013.01); G16H 30/40 (2018.01); G16H 50/20 (2018.01); G06T 2200/04 (2013.01); G06T 2207/10016 (2013.01); G06T 2207/10081 (2013.01); G06T 2207/10121 (2013.01); G06T 2207/20056 (2013.01); G06T 2207/30061 (2013.01); G06T 2207/30104 (2013.01); G06T 2210/41 (2013.01);
Abstract

Described herein are systems, methods, and computer-readable medium for detecting a perfusion abnormality of a subject. In one embodiment, a method includes the following: obtaining, by dynamic radiography, imaging data for a dynamic series of a plurality of x-ray images that include areas of a subject corresponding to pulmonary vasculature; identifying, based on the imaging data, a dynamic signal corresponding to changing blood volume during the cardiac cycle of the subject; decomposing the dynamic signal into periodic components in frequency space; identifying, from the periodic components in frequency space, signals oscillating at the heart rate of the subject; generating, based on the identified signals oscillating at the heart rate of the subject, a perfusion map representation corresponding to pulmonary tissue perfusion in the subject; and detecting, based at least in part on the generated perfusion map representation, a perfusion abnormality of the subject.


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