The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2025

Filed:

May. 25, 2022
Applicant:

University of Shanghai for Science and Technology, Shanghai, CN;

Inventors:

Weijie Li, Shanghai, CN;

Jing Shen, Shanghai, CN;

Yanbin Qin, Shanghai, CN;

Zhixin Li, Shanghai, CN;

Hongli Yan, Shanghai, CN;

Qin Qi, Shanghai, CN;

Baolin Liu, Shanghai, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 1/162 (2025.01); A01N 1/144 (2025.01);
U.S. Cl.
CPC ...
A01N 1/162 (2025.01); A01N 1/144 (2025.01);
Abstract

A method, system and device for programmed cell freezing is disclosed. The method includes: S1, acquiring a cooling rate k and a temperature distribution function T=a×h+b×h+c of a heat preservation chamber containing liquid nitrogen; S2, controlling a cell preservation tube to lower in the chamber at a speed of v=(k−b)/2ah, and acquiring temperatures Tand Tinside and outside the tube at a same time and at a same height in real time during the lowering of the tube; S3, determining whether a difference Δt between Tand Texceeds a preset temperature difference threshold, if yes, proceeding to S4, and if no, proceeding to S2 until the tube reaches a position corresponding to a preset temperature T; and S4, controlling the cell preservation tube to stop until the difference Δt between Tand Tis less than or equal to the temperature difference threshold, and continuing S2.


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