The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Dec. 03, 2020
Biofire Diagnostics, Llc, Salt Lake City, UT (US);
Thomas Charles Robbins, Salt Lake City, UT (US);
Theodore Allan Wilson, Salt Lake City, UT (US);
Charles Benjamin Cox, Sandy, UT (US);
Jay Jones, Salt Lake City, UT (US);
Benjamin William Galvin, Salt Lake City, UT (US);
Amber Cooper Kiser, Taylorsville, UT (US);
BIOFIRE DIAGNOSTICS, LLC, Salt Lake City, UT (US);
Abstract
Techniques are provided for generating an array-specific range of Tm values to be used for calling a sample in a given array positive or negative for a target nucleic acid sequence. A sample well in an array is provided with a control sample containing a control nucleic acid sequence. The control sample is amplified by thermal cycling the sample well. A Tm value for the control sample is identified and compared to an expected Tm value for the control nucleic acid sequence to calculate a relationship between the identified control Tm value and the expected control Tm value. By applying this relationship to an expected Tm value for a target nucleic acid sequence, an array-specific range of Tm values for the target nucleic acid sequence is generated and can be used for calling an experimental sample in the same array positive or negative for the target nucleic acid sequence.