The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Oct. 09, 2020
Asociación Centro DE Investigación Cooperativa En Biomateriales—cic Biomagune, San Sebastián, ES;
Fundacion Tecnalia Research & Innovation, Derio-Bizkaia, ES;
Valery Pavlov, Astigarraga, ES;
Veronica Mora Sanz, Saragossa, ES;
Nerea Briz Iceta, San Sebastián, ES;
Laura Saa Peña, San Sebastián, ES;
ASOCIACIÓN CENTRO DE INVESTIGACIÓN COOPERATIVA EN BIOMATERIALES—CIC BIOMAGUNE, San Sebastian, ES;
FUNDACION TECNALIA RESEARCH & INNOVATION, Derio-Bizkaia, ES;
Abstract
The present invention provides metallic nanocluster (NC)—antibody (Ab) conjugate, wherein the NC has an average size lower than 3 nm and the conjugate: (a) comprises one single NC, (b) the antibody maintains the binding ability; and (c) has a catalytic activity selected from peroxidase-like and photocatalytic activity. The invention also provides a process for the preparation of the conjugate as well as compositions, kits and uses in therapy and diagnostics. Advantageously, the conjugate of the invention shows improved catalytic activity, providing a remarkable improved immunoassay's sensitivity.