The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Jul. 14, 2021
Applicant:

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Ikenna Okereke, Galveston, TX (US);

Richard Pyles, Galveston, TX (US);

Aaron Miller, Galveston, TX (US);

Catherine Hamilton, Galveston, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/686 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/686 (2013.01); C12Q 2600/112 (2013.01);
Abstract

The present invention includes a method of detecting and treating a patient suspected of having Barrett's esophagus comprising: obtaining a biological sample from an esophagus of the patient; determining a microbiome in the biological sample by detecting the presence of bacteria by plasmid dilution verification or quantitative polymerase chain reaction (qPCR); wherein if the patient has a microbiome indicative of an increased risk of esophageal cancer threating the patient with at least one of: removing at least part of the esophagus, esophagectomy probiotic therapy, or chemically targeting elimination of bacteria indicative of an increased risk of esophageal cancer.


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