Method for detecting the presence, identification and quantification in a blood sample of anticoagulants which are blood coagulation enzymes inhibitors, and means for the implementation thereof

Abstract

Disclosed is an in vitro method for detecting, in a biological sample, the presence of a blood coagulation enzyme inhibitor selected, independently, from factor Xa and factor IIa, the method including the step of making one or more competitive kinetics measurement(s) by carrying out a competitive enzymatic assay and implementing one or more types of classification or regression decision models obtained by training automated supervised learning models. The method may include the identification in the biological sample of an inhibitor in question, or even its characterization, or even its quantification. Also disclosed is a data processing system or device including implementation for at least part of the method, a computer program or storage medium which can be read by a computer or appropriate data, and a suitable kit.