The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Aug. 19, 2022
Jilin University, Changchun, CN;
Zhenzhen Huang, Changchun, CN;
Xiaoyu Geng, Changchun, CN;
Ruisong Xue, Changchun, CN;
Shiyong Teng, Changchun, CN;
Jinshuo Li, Changchun, CN;
Yanmei Liu, Changchun, CN;
Wensheng Yang, Changchun, CN;
Jilin University, Changchun, CN;
Abstract
The present disclosure provides use of guar gum, a fluorescence-enhanced gold nanocluster, a method for detecting α-glucosidase (α-Glu), and a method for screening an α-Glu inhibitor, and belongs to the technical field of nanoscale biosensing. The present disclosure provides the use of the guar gum in improving a fluorescence emission intensity of a gold nanocluster. In the present disclosure, the guar gum is a natural high-molecular polymer extracted from seeds of guar, a leguminous plant, and has a low price, no toxicity, and desirable biocompatibility. The guar gum includes galactose and mannose, is rich in hydroxyl groups in a molecular backbone, and can improve a fluorescence emission intensity of the gold nanocluster. On this basis, detection of an α-Glu activity and screening of an α-Glu inhibitor can be realized with a high sensitivity and low cost.