The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Oct. 09, 2023
Applicant:

Adma Biomanufacturing, Llc, Boca Raton, FL (US);

Inventors:

Adam S. Grossman, Saddle River, NJ (US);

James Mond, Silver Spring, MD (US);

Jerrold B. Grossman, Saddle River, NJ (US);

Dov A. Goldstein, New York, NY (US);

Assignee:

ADMA BIOMANUFACTURING, LLC, Boca Raton, FL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/155 (2006.01); A61K 39/42 (2006.01); A61K 45/06 (2006.01); C07K 16/06 (2006.01); C07K 16/08 (2006.01); C07K 16/10 (2006.01); C07K 16/12 (2006.01); G01N 33/68 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/06 (2013.01); A61K 39/155 (2013.01); A61K 39/39516 (2013.01); A61K 39/42 (2013.01); A61K 45/06 (2013.01); C07K 16/08 (2013.01); C07K 16/1002 (2023.08); C07K 16/1009 (2013.01); C07K 16/1027 (2013.01); C07K 16/1203 (2013.01); C07K 16/1232 (2013.01); C07K 16/1242 (2013.01); C07K 16/1271 (2013.01); C07K 16/1275 (2013.01); C07K 16/1282 (2013.01); C07K 16/1285 (2013.01); C07K 16/1289 (2013.01); G01N 33/6854 (2013.01); A61K 2039/507 (2013.01); C07K 2317/10 (2013.01); C07K 2317/21 (2013.01); C07K 2317/31 (2013.01); C07K 2317/76 (2013.01); Y02A 50/30 (2018.01);
Abstract

The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).


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