The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Oct. 15, 2019
Applicant:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Inventors:
Cigall Kadoch, Tiburon, CA (US);
Nazar Mashtalir, Allston, MA (US);
Brittany C. Michel, Brookline, MA (US);
Andrew D′Avino, Boston, MA (US);
Assignee:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); A61K 38/00 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4702 (2013.01); G01N 33/6875 (2013.01); A61K 38/00 (2013.01); C07K 2319/41 (2013.01); C07K 2319/42 (2013.01); C07K 2319/43 (2013.01); G01N 2500/04 (2013.01);
Abstract
The present invention is based, in part, on the novel discovery of the architecture and assembly pathway of three different classes of mammalian SWI/SNF complexes, compositions comprising the isolated modified SWI/SNF complexes, and methods of screening for modulators of the function and/or stability of same.