The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Sep. 25, 2023
Cornell University, Ithaca, NY (US);
Tri-institutional Therapeutics Discovery Institute, New York, NY (US);
Gang Lin, Forest Hills, NY (US);
Carl Nathan, Larchmont, NY (US);
Laura Kirkman, New York, NY (US);
Wenhu Zhan, Elmhurst, NY (US);
Trevor Morgan, Royston, GB;
Kenjiro Sato, Kanagawa, JP;
Ryoma Hara, Tokyo, JP;
Masanori Kawasaki, Tokyo, JP;
Toshihiro Imaeda, Kanagawa, JP;
Akinori Toita, Kanagawa, JP;
Rei Okamoto, Kanagawa, JP;
Takafumi Yukawa, Kanagawa, JP;
Kazuyoshi Aso, Kanagawa, JP;
Tzu-Tshin Wong, Acton, MA (US);
John D. Ginn, New Milford, CT (US);
Michael A. Foley, New York, NY (US);
CORNELL UNIVERSITY, Ithaca, NY (US);
TRI-INSTITUTIONAL THERAPEUTICS DISCOVERY INSTITUTE, New York, NY (US);
Abstract
The compounds of the present invention are represented by the following compounds having Formula I and Formula (I′): where the substituents R, R, R, R, R, R, R', R″, X, Y, and Z are as defined herein and where the substituents R, R, R, R, R, R', R″, X, Y, and Z are as defined herein. These compounds are used in the treatment of bacterial infections, parasite infections, fungal infections, cancer, immunologic disorders, autoimmune disorders, neurodegenerative diseases and disorders, inflammatory disorders, or muscular dystrophy or for providing immunosuppression for transplanted organs or tissues.