The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Jan. 31, 2020
Applicant:
Ripple Therapeutics Corporation, Toronto, CA;
Inventors:
Ian Charles Parrag, Mississauga, CA;
Matthew Alexander John Statham, Milton, CA;
Emma-Louise Elizabeth Moore, Mississauga, CA;
Bahareh Khalili, Mississauga, CA;
Judith Anne Williams, Toronto, CA;
Elizabeth Poloz, Kitchener, CA;
Boris Gorin, Oakville, CA;
Assignee:
Ripple Therapeutics Corporation, Toronto, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07J 5/00 (2006.01); A61K 8/00 (2006.01); A61P 19/02 (2006.01); B29C 35/02 (2006.01); B29C 49/00 (2006.01); B29K 105/00 (2006.01);
U.S. Cl.
CPC ...
C07J 5/0076 (2013.01); A61K 8/00 (2013.01); A61P 19/02 (2018.01); B29C 35/02 (2013.01); B29C 49/0006 (2022.05); B29K 2105/0035 (2013.01); C07B 2200/13 (2013.01);
Abstract
The disclosure features polymorphs of a prodrug dimer of dexamethasone linked at the 21-C and 21'-C carbons via a carbonate-triethylene glycol-carbonate linker. Also disclosed are pharmaceutical compositions and articles comprising said polymorphs, and the use thereof in the treatment of a disease or condition, e.g. via the extended or controlled release of dexamethasone from said articles.