The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Nov. 22, 2021
Applicant:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Inventors:

Noriko Sato, Potomac, MD (US);

Haitao Wu, Rockville, MD (US);

Gary L. Griffiths, North Potomac, MD (US);

Peter L. Choyke, Rockville, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 51/12 (2006.01); C07B 59/00 (2006.01); C07F 7/00 (2006.01); C12Q 1/16 (2006.01); G01N 33/60 (2006.01);
U.S. Cl.
CPC ...
C07F 7/003 (2013.01); A61K 51/0478 (2013.01); A61K 51/1203 (2013.01); C07B 59/004 (2013.01); C12Q 1/16 (2013.01); G01N 33/60 (2013.01); G01N 2458/30 (2013.01);
Abstract

The invention provides a method of preparing aZr-oxine complex of the formula The invention also provides a method of labeling a cell with theZr-oxine complex and a method for detecting a biological cell in a subject comprising administering theZr-oxine complex to the subject.


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