The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Nov. 01, 2024
Applicant:

Cellarity, Inc., Somerville, MA (US);

Inventors:

Robert Brian Nicewonger, Tyngsboro, MA (US);

Mauricio Cortes, Wellesley, MA (US);

Colin Diner, Somerville, MA (US);

Ragy Haddad, Cambridge, MA (US);

Sriram Krishnamoorthy, Acton, MA (US);

Na Li, Winchester, MA (US);

Frank Lovering, Acton, MA (US);

Kristen Marino, Stoneham, MA (US);

Samuel Miller, Cambridge, MA (US);

Qing Tang, Boxborough, MA (US);

Atli Thorarensen, Stow, MA (US);

Ravi Ujjinamatada, Lexington, MA (US);

David Zhang, West Roxbury, MA (US);

Assignee:

Cellarity, Inc., Somerville, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

The present disclosure provides DCN-1 modulating compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions, and their use for treating sickle cell disorders, diseases, and conditions. Such compounds are of Formula I: or a pharmaceutically acceptable salt thereof.


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