The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Oct. 10, 2019
Applicant:
Albert Einstein College of Medicine, Bronx, NY (US);
Inventors:
Ana Maria Cuervo, Bronx, NY (US);
Evripidis Gavathiotis, Flushing, NY (US);
Assignee:
ALBERT EINSTEIN COLLEGE OF MEDICINE, Bronx, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 263/57 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 263/57 (2013.01); C07D 413/12 (2013.01);
Abstract
Compounds and pharmaceutically acceptable salts thereof of Formula I are disclosed. The variables, e.g. R-R, X, and Y are defined herein. Certain compounds and salts of Formula I are active as CMA modulators. The disclosure provides pharmaceutical compositions containing a compound of Formula I and methods of treating disorders responsive to CMA modulation.