The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Jul. 30, 2020
Applicant:
Oregon State University, Corvallis, OR (US);
Inventors:
Siva Kumar Kolluri, Corvallis, OR (US);
Nancy I. Kerkvliet, Corvallis, OR (US);
Sebastian Bernales, San Francisco, CA (US);
Jit Chakravarty, Edmond, OK (US);
Brahmam Pujala, Greater Noida, IN;
Pasha Khan, New Delhi, IN;
Varun Kumar, New Delhi, IN;
Abhinandan Danodia, Greater Noida, IN;
Gonzalo Ureta, Santiago, CL;
Assignee:
Oregon State University, Corvallis, OR (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/06 (2006.01); C07D 209/12 (2006.01); C07D 307/80 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 403/04 (2006.01); C07D 405/04 (2006.01); C07D 405/06 (2006.01); C07D 409/04 (2006.01); C07D 471/06 (2006.01); C07D 471/16 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 235/06 (2013.01); C07D 209/12 (2013.01); C07D 307/80 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/06 (2013.01); C07D 409/04 (2013.01); C07D 471/06 (2013.01); C07D 471/16 (2013.01); C07D 487/04 (2013.01);
Abstract
Small molecule AhR ligands are disclosed. The ligands can induce the differentiation of Tr1 cells to suppress pathogenic immune responses without inducing nonspecific immune suppression. Methods of treatment of autoimmune diseases using the AhR ligands are also disclosed.