The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Sep. 21, 2020
Applicant:

Microsensor Labs, Llc, Chicago, IL (US);

Inventors:

Peng Liu, Chicago, IL (US);

Zerikhun Filatov, Chicago, IL (US);

Assignee:

Microsensor Labs, LLC, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 1/00 (2006.01); B01L 3/00 (2006.01); C12M 1/00 (2006.01); C12M 1/26 (2006.01); G01N 15/0227 (2024.01); G01N 15/10 (2024.01); G01N 15/1031 (2024.01); G01N 33/543 (2006.01); G06T 7/70 (2017.01); G06V 20/69 (2022.01);
U.S. Cl.
CPC ...
B01L 3/502761 (2013.01); C12M 33/00 (2013.01); C12M 47/04 (2013.01); G01N 15/0227 (2013.01); G01N 15/1031 (2013.01); G01N 33/54326 (2013.01); G06T 7/70 (2017.01); G06V 20/698 (2022.01); B01L 2200/0668 (2013.01); B01L 2300/0663 (2013.01); B01L 2300/0816 (2013.01); B01L 2400/043 (2013.01); G01N 2015/1028 (2024.01); G06T 2207/10056 (2013.01); G06T 2207/30024 (2013.01); G06T 2207/30072 (2013.01);
Abstract

A system and method for detection of cells and sorting of cells are disclosed. Target cells, such as circulating tumor cells (CTCs) or antigen-specific antibody producing circulating memory B cells from COVID-19 patients, may be of interest. Magnetic beads may be bound to the target cells. After which, the bead-bound target cells may be identified using an applied magnetic field. In one example, magnetic sensors may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. In another example, an optical sensor may be used to detect movement of the bead-bound target cells responsive to an applied magnetic field. Further, separate from identification of the target cells, the bead-bound target cells may be sorted using an applied magnetic field. In this way, a magnetic field may be used for target cell identification and target cell sorting in order to detect and collect target cells of interest at the single-cell resolution.


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