The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Nov. 28, 2022
University of Maryland, College Park, College Park, MD (US);
Wolfgang Losert, Bethesda, MD (US);
John T. Fourkas, Bethesda, MD (US);
Meghan Driscoll, Berwyn Heights, MD (US);
Floyd Bates, Ii, Upper Marlboro, MD (US);
Xiaoyu Sun, Laurel, MD (US);
Can Guven, Hilsboro, OR (US);
Joshua Parker, Washington, DC (US);
University of Maryland, College Park, MD (US);
Abstract
The invention provides method of guiding unidirectional movement of a cell comprising exposing the cell to a surface comprising an asymmetric, three-dimensional pattern of one or a plurality of topographical elements for a time period sufficient to bias actin polymerization within the cell. The invention also provides methods of inducing directional movement of a cell, and methods of harnessing an actin wave within a cell. In addition, the invention provides compositions comprising a contact side, wherein at least a portion of the contact side comprises a cell contact portion comprising an asymmetric, three-dimensional pattern of one or a plurality of topographical elements, and methods of inducing healing of a wound of a subject comprising contacting the wound with the composition.