The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Aug. 26, 2019
Applicant:
Smartdyelivery Gmbh, Jena, DE;
Inventors:
Christoph Enzensperger, Jena, DE;
Marc Lehmann, Jena, DE;
Assignee:
SMARTDYELIVERY GMBH, Jena, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/22 (2006.01); A61K 31/553 (2006.01); A61K 45/06 (2006.01); A61K 47/54 (2017.01); A61K 47/69 (2017.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 47/22 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01); A61K 47/545 (2017.08); A61K 47/6937 (2017.08); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2320/32 (2013.01);
Abstract
The invention relates to inhibitors of the PKC signaling pathway for use in the treatment of septic cholestasis, wherein the inhibitors are targeted into the liver by a selective nanostructured delivery system, wherein the selective nanostructured delivery system comprises at least one polymethine dye and at least one polymer and/or at least one lipid and/or at least one virus-like particle, wherein the at least one polymethine dye is a symmetrical or asymmetrical polymethine.