The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

May. 03, 2021
Applicants:

Purdue Research Foundation, West Lafayette, IN (US);

Monash University, Clayton, AU;

Inventors:

Qi Zhou, West Lafayette, IN (US);

Maizbha Uddin Ahmed, West Lafayette, IN (US);

Jian Li, Carnegie, AU;

Mohammad Abul Kalam Azad, Melton South, AU;

Assignees:

Purdue Research Foundation, West Lafayette, IN (US);

Monash University, Clayton, AU;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/7036 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 38/12 (2006.01); A61P 11/00 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7036 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01); A61K 9/1682 (2013.01); A61K 38/12 (2013.01); A61P 11/00 (2018.01); A61P 31/04 (2018.01);
Abstract

The present disclosure generally relates to a method for reducing the toxicity of inhaled polymyxins as a therapeutic agent comprising the step of co-administration of an aminoglycoside; a method for improving the aerosolization of an aminoglycoside comprising the step of combination formulation with a polymyxin; and a process for manufacturing a dry powder composition comprising a polymyxin and aminoglycoside. Pharmaceutical compositions and methods of treatment for lung infections are within the scope of this invention.


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