The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Nov. 20, 2020
Applicants:

Ab Science, Paris, FR;

Université Paris Cité, Paris, FR;

Assistance Publique Hopitaux DE Paris, Paris, FR;

Institut National DE LA Sante ET DE LA Recherche Medicale, Paris, FR;

Imagine Institut Des Maladies Genetiques Necker Enfants Malades, Paris, FR;

Inventors:

Alain Moussy, Paris, FR;

Jean-Pierre Kinet, Lexington, MA (US);

Olivier Hermine, Paris, FR;

Thiago Trovati Maciel, Villeneuve-le-Roi, FR;

Slimane Allali, Meudon, FR;

Rachel Rignault-Bricard, Choisy-le-Roi, FR;

Caroline Carvalho, Emerainville, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/426 (2006.01); A61K 31/496 (2006.01); A61P 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61K 31/496 (2013.01); A61P 7/00 (2018.01);
Abstract

A 2-aminoarylthiazole derivative or a pharmaceutically acceptable salt or solvate thereof, in particular masitinib or a pharmaceutically acceptable salt or solvate thereof, for use in the treatment of sickle cell disease in a patient in need thereof. Also, a 2-aminoarylthiazole derivative or a pharmaceutically acceptable salt or solvate thereof, in particular masitinib or a pharmaceutically acceptable salt or solvate thereof, for use in the prevention and/or treatment of acute chest syndrome (ACS) in a sickle cell disease patient in need thereof.


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