The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2025
Filed:
Mar. 20, 2020
BE Pharbel Manufacturing, Courcelles, BE;
Geoffrey De Bilde, Pont-à-Celles, BE;
Pierre Sacre, Maizeret, BE;
Jonathan Goole, Woluwe-Saint-Lambert, BE;
Karim Amighi, Woluwe Saint-Pierre, BE;
Olivier Laloux, Court-Saint-Etienne, BE;
Georges Guillaume, Ophain, BE;
Vincent Stephenne, Baisy-Thy, BE;
BE PHARBEL MANUFACTURING, Courcelles, BE;
Abstract
A controlled-release multilayer microparticle containing a pharmaceutically active compound, which is intended for oral administration or direct administration in the stomach, which may be done using a liquid pharmaceutical composition containing the microparticle. The microparticle may include: a core that includes the pharmaceutically active compound, which may be pramipexole; a controlled-release intermediate coating layer; and an outmost external protection coating layer surrounding the controlled-release intermediate coating layer. The external protection coating layer may include a mixture of: a hydrophilic gastro-soluble component which is insoluble in aqueous media at a pH of between 6.5 and 7.5; and a hydrophobic and/or insoluble component. Also disclosed are a liquid pharmaceutical composition containing the microparticles, a kit for the preparation of the liquid pharmaceutical composition, a pharmaceutical solid composition reconstitutable as the liquid composition, a process of preparing the liquid composition, and a method for treating disease with the liquid composition.