The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2025

Filed:

Dec. 23, 2020
Applicant:

Daicel Corporation, Osaka, JP;

Inventors:

Masahiko Shimizu, Tokyo, JP;

Ryuji Saitou, Tokyo, JP;

Katsunori Makizawa, Tokyo, JP;

Assignee:

DAICEL CORPORATION, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/34 (2006.01); A61Q 19/00 (2006.01); B01D 3/42 (2006.01); C07C 29/141 (2006.01); C07C 29/60 (2006.01); C07C 29/80 (2006.01); C07C 29/84 (2006.01); C07C 31/20 (2006.01);
U.S. Cl.
CPC ...
A61K 8/345 (2013.01); A61Q 19/00 (2013.01); A61Q 19/007 (2013.01); B01D 3/4205 (2013.01); C07C 29/141 (2013.01); C07C 29/60 (2013.01); C07C 29/80 (2013.01); C07C 29/84 (2013.01); C07C 31/207 (2013.01); A61K 2800/10 (2013.01);
Abstract

Provided is a method capable of manufacturing high-purity 1,3-butylene glycol having a high potassium permanganate test value, a very low content of low boiling point components, and a high initial boiling point with a high recovery rate. The method for manufacturing 1,3-butylene is a method for obtaining purified 1,3-butylene glycol from a crude reaction liquid containing 1,3-butylene glycol. In a dehydration column used in a dehydration step, a liquid feed containing 1,3-butylene glycol and water with an acetaldehyde content of 1000 ppm or lower and a crotonaldehyde content of 400 ppm or lower is distilled under a condition of a reflux ratio of higher than 0.3, and a liquid concentrated with a low boiling point component containing water is distilled off from above a feed tray. In a product column used in a product distillation step, a 1,3-butylene glycol liquid feed with an acetaldehyde content of 500 ppm or lower and a crotonaldehyde content of 200 ppm or lower is distilled under a condition of a reflux ratio of higher than 0.1.


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