The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2025
Filed:
Jan. 23, 2025
Wuhan University, Wuhan, CN;
WUHAN UNIVERSITY, Wuhan, CN;
Abstract
The disclosure belongs to the field of genetic testing and biomedicine, relating to a method for constructing a prognostic model of hepatoma and an application thereof, comprising 1) obtaining and identifying fibroblasts with high FAP expression; 2) obtaining and identifying TAMs; 3) analyzing co-localization between fibroblasts with high FAP expression obtained and the TAMs obtained previously; 4) communicating and analyzing the fibroblasts with high FAP expression after the localization in the Step 3) with TAMs to obtain CCC ligand-receptor genes; 5) screening the CCC ligand-receptor genes obtained previously based on machine learning to obtain key CCC ligand-receptor genes; and 6) constructing a prognostic model of hepatoma according to the key CCC ligand-receptor genes obtained in the Step 5). The present disclosure provides a method for constructing a prognostic model of hepatoma that can be applied to auxiliary judgment of the prognosis of hepatoma patients and an application thereof.