The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

Sep. 09, 2021
Applicants:

Chang Gung University, Taoyuan, TW;

Chang Gung Memorial Hospital, Linkou, Taoyuan, TW;

Inventors:

Shin-Ru Shih, New Taipei, TW;

Kuan-Ting Liu, Taoyuan, TW;

Guang-Wu Chen, New Taipei, TW;

Chung-Guei Huang, Taoyuan, TW;

Kar-Yee Yu, Taoyuan, TW;

Hou-Chen Lee, Taoyuan, TW;

Peng-Nien Huang, Taoyuan, TW;

Yu-Nong Gong, Taoyuan, TW;

Rei-Lin Kuo, Taoyuan, TW;

Chih-Ching Wu, Taoyuan, TW;

Yu-An Kung, Taoyuan, TW;

Sheng-Yu Huang, Taoyuan, TW;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/215 (2006.01); G01N 33/538 (2006.01); G01N 33/543 (2006.01); G01N 33/569 (2006.01); G06N 7/00 (2023.01);
U.S. Cl.
CPC ...
G01N 33/56983 (2013.01); G01N 33/538 (2013.01); G01N 33/54366 (2013.01); G01N 2800/26 (2013.01); G06N 7/00 (2013.01);
Abstract

A method for determining immune competence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) includes obtaining a blood sample from a subject in need thereof, detecting, in the blood sample, levels of binding antibodies against SARS-CoV-2 spike S1 protein and its receptor binding domain (RBD), and calculating a weighted value using a regression model. Another method for determining immune competence against SARS-CoV-2 is also disclosed.


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