The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

Dec. 20, 2022
Applicant:

Academia Sinica, Taipei, TW;

Inventors:

Pei-Kuen Wei, Taipei, TW;

Sheng-Hann Wang, Chaozhou Township, Pingtung County, TW;

Ting-Wei Chang, New Taipei, TW;

Assignee:

ACADEMIA SINICA, Taipei, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 21/552 (2014.01); G01N 21/17 (2006.01);
U.S. Cl.
CPC ...
G01N 21/554 (2013.01); G01N 2021/177 (2013.01);
Abstract

A detection method and a detection system for detecting objects of interest attached to a surface of a plurality of reporters, wherein the plurality of reporters are flowing in a microfluidic chip and illuminated by a light source. The detection method has following steps: obtaining a plurality of local surface plasmon resonance (LSPR) spectral images of each the plurality of the reporters individually, wherein each of the LSPR spectral images has a brightness of a long wavelength band (B) and a brightness of a short wavelength band (B); calculating a spectral image brightness contrast γ for each of the LSPR spectral images, wherein and, defining a positive threshold for |γ|≥0.1.


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