The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2025
Filed:
Jul. 24, 2019
Zeon Corporation, Tokyo, JP;
Taichi Sawaguchi, Tokyo, JP;
ZEON CORPORATION, Tokyo, JP;
Abstract
Provided is a pre-filled syringe that can inhibit protein aggregation in a protein solution formulation while also reducing the produced amount of a decomposition product of a non-ionic surfactant after long-term storage. The pre-filled syringe includes: a barrel formed of a resin containing a hydrogenated cycloolefin ring-opened polymer and/or a copolymer of a cycloolefin and a chain olefin; a sealing member sealing a nozzle of the barrel; a gasket housed inside the barrel; and a plunger performing a movement operation of the gasket, and contains a protein solution formulation in a space defined by the sealing member, the gasket, and a region that is part of an inner wall surface of the barrel. The protein solution formulation has a non-ionic surfactant concentration of more than 0 mg/mL and less than 0.05 mg/mL.