The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

Apr. 16, 2020
Applicant:

Bachem Holding Ag, Bubendorf, CH;

Inventors:

Ralf Eisenhuth, Basel, CH;

Daniel Samson, Leonding, AT;

Ralph O. Schoenleber, Lupsingen, CH;

Patrizia Marchetti, Aarau, CH;

Assignee:

BACHEM HOLDING AG, Bubendorf, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/113 (2006.01); B01D 61/02 (2006.01); B01J 19/00 (2006.01); C07K 1/34 (2006.01); C07K 7/06 (2006.01); C07K 7/16 (2006.01);
U.S. Cl.
CPC ...
C07K 1/1133 (2013.01); B01D 61/027 (2013.01); B01J 19/0033 (2013.01); C07K 1/34 (2013.01); C07K 7/06 (2013.01); C07K 7/16 (2013.01); B01J 2219/00164 (2013.01); B01J 2219/00186 (2013.01);
Abstract

A method and apparatus for the manufacture of disulfide bonded peptides is provided, wherein a solution of an oxidizing agent and a solution of a peptide comprising at least two sulfhydryl groups are added simultaneously into a reaction vessel under such conditions that the average concentration of the oxidizing agent inside the reaction vessel is essentially zero during simultaneous addition.


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