The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

Jul. 06, 2021
Applicant:

Almac Discovery Limited, Craigavon, GB;

Inventors:

Peter Hewitt, Craigavon, GB;

Mary Melissa Mcfarland, Craigavon, GB;

James Samuel Shane Rountree, Craigavon, GB;

Frank Burkamp, Craigavon, GB;

Christina Bell, Craigavon, GB;

Lauren Proctor, Craigavon, GB;

Matthew Duncan Helm, Craigavon, GB;

Colin O'Dowd, Craigavon, GB;

Timothy Harrison, Craigavon, GB;

Assignee:

ALMAC DISCOVERY LIMITED, Craigavon, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61P 21/00 (2006.01); A61P 25/16 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 491/10 (2006.01);
U.S. Cl.
CPC ...
C07D 401/06 (2013.01); A61P 21/00 (2018.01); A61P 25/16 (2018.01); A61P 35/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 491/10 (2013.01);
Abstract

The present invention relates to compounds of Formula (I) that are useful as inhibitors of the activity of the ubiquitin specific protease USP19. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in therapy.


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