The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2025
Filed:
Nov. 30, 2022
Pfizer Inc., New York, NY (US);
Leanne Marie Buzon, Stonington, CT (US);
Kimberly O'Keefe Cameron, Niantic, CT (US);
Kevin Francis Deboyace, Mystic, CT (US);
Kevin James Filipski, Reading, MA (US);
David Andrew Griffith, Sudbury, MA (US);
Bethany Lyn Kormos, Somerville, MA (US);
Shenping Liu, Waterford, CT (US);
Luis Angel Martinez Alsina, Gales Ferry, CT (US);
Matthew Richard Reese, Mystic, CT (US);
Rachel Jane Roth Flach, Rockland, MA (US);
Yuan Zhang, Mansfield, MA (US);
Pfizer Inc., New York, NY (US);
Abstract
Described herein are compounds of Formula I, wherein the variables are defined herein, their use as branched-chain alpha keto acid dehydrogenase kinase inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, diabetes, kidney disease, NASH and heart failure.