The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2025
Filed:
May. 05, 2020
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Jian Jin, New York, NY (US);
Steven Burakoff, New York, NY (US);
H. Umit Kaniskan, New York, NY (US);
Sansana Sawasdikosol, New York, NY (US);
He Chen, New York, NY (US);
Joshua Brody, New York, NY (US);
Nina Bhardwaj, New York, NY (US);
Assignee:
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 47/55 (2017.01); A61K 39/395 (2006.01); A61K 47/54 (2017.01); A61P 35/00 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
A61K 47/55 (2017.08); A61K 39/3955 (2013.01); A61K 47/545 (2017.08); A61P 35/00 (2018.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 417/14 (2013.01); C07D 487/04 (2013.01);
Abstract
Disclosed are Hematopoietic Progenitor Kinase 1 (HPK1) degradation/disruption compounds including a HPK1 ligand, a degradation/disruption tag and a linker, and methods for use of such compounds in the treatment of HPK1-mediated diseases.