The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2025
Filed:
Nov. 02, 2021
Applicant:
Astellas Institute for Regenerative Medicine, Westborough, MA (US);
Inventors:
Erin Anne Kimbrel, Sudbury, MA (US);
Robert P. Lanza, Clinton, MA (US);
Jianlin Chu, Bedford, MA (US);
Nicholas Arthur Kouris, Hudson, MA (US);
Assignee:
Astellas Institute for Regenerative Medicine, Westborough, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); C12N 5/0775 (2010.01); C12N 5/0789 (2010.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); C12N 5/0647 (2013.01); C12N 5/0662 (2013.01); C12N 2501/115 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/26 (2013.01); C12N 2506/02 (2013.01); C12N 2506/11 (2013.01); C12N 2533/90 (2013.01);
Abstract
The present invention generally relates to novel preparations of mesenchymal stromal cells (MSCs) derived from hemangioblasts, methods for obtaining such MSCs, and methods of treating a pathology using such MSCs. The methods of the present invention produce substantial numbers of MSCs having a potency-retaining youthful phenotype, which are useful in the treatment of pathologies.