The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

Jul. 30, 2021
Applicants:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Inventors:

Eric Sorscher, Atlanta, GA (US);

Haian Fu, Decatur, GA (US);

Huw Davies, Suwanee, GA (US);

Jeong Hong, Decatur, GA (US);

Yuhong Du, Atlanta, GA (US);

Andras Rab, Atlanta, GA (US);

Candela Manfredi, Atlanta, GA (US);

Xun Yang, Atlanta, GA (US);

Zhi Ren, Atlanta, GA (US);

Assignees:

Emory University, Atlanta, GA (US);

Children's Healthcare of Atlanta, Inc., Atlanta, GA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/427 (2006.01); A61K 31/4155 (2006.01); A61K 31/433 (2006.01);
U.S. Cl.
CPC ...
A61K 31/427 (2013.01); A61K 31/4155 (2013.01); A61K 31/433 (2013.01);
Abstract

This disclosure relates to compounds that are cystic fibrosis transmembrane conductance regulator (CFTR) modulators and pharmaceutical compositions containing the same. In certain embodiments, this disclosure relates to methods of managing a CFTR related disease or condition or respiratory distress comprising administering an effective amount of a CFTR modulator disclosed herein to a subject in need thereof.


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