The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2025

Filed:

May. 28, 2020
Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Zeeshan Syedain, Minneapolis, MN (US);

Robert Tranquillo, Arden Hills, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/24 (2006.01); A61L 27/22 (2006.01); A61L 27/24 (2006.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); B29D 23/00 (2006.01); B29K 105/00 (2006.01); C12M 1/12 (2006.01); C12M 3/00 (2006.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
A61F 2/2415 (2013.01); A61F 2/2418 (2013.01); A61L 27/225 (2013.01); A61L 27/24 (2013.01); A61L 27/3691 (2013.01); A61L 27/3817 (2013.01); A61L 27/3839 (2013.01); A61L 27/52 (2013.01); B29D 23/00 (2013.01); C12M 21/08 (2013.01); C12M 23/06 (2013.01); C12M 25/00 (2013.01); C12N 5/0656 (2013.01); A61F 2220/0075 (2013.01); A61F 2240/001 (2013.01); A61L 2430/20 (2013.01); A61L 2430/40 (2013.01); B29K 2089/00 (2013.01); B29K 2105/0061 (2013.01);
Abstract

This disclosure provides a tissue-engineered transcatheter vein valve and methods of making such a tissue-engineered transcatheter vein valve. Methods of making the valve include casting or molding a polymer into a tubular structure having a first end and a second end, where the first end of the tubular structure is cast or molded around a tubular support structure and where the second end of the tubular structure is cast or molded in the absence of the support structure; everting the polymer at the second end through the support structure; anchoring the second end of the tubular structure to the support structure at a first position and a second position, where the anchored first position and the anchored second position result in commissures, forming leaflets therebetween.


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