The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Dec. 06, 2024
Applicant:

Insitro, Inc., South San Francisco, CA (US);

Inventors:

Hervé Marie-Nelly, San Francisco, CA (US);

Jeevaa Velayutham, Shah Alam, MY;

Zachary Phillips, San Francisco, CA (US);

Shengjiang Tu, Foster City, CA (US);

Assignee:

Insitro, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06T 7/00 (2017.01); A61B 5/00 (2006.01); G01N 15/1429 (2024.01); G16H 20/00 (2018.01);
U.S. Cl.
CPC ...
G06T 7/0012 (2013.01); A61B 5/4848 (2013.01); G01N 15/1429 (2013.01); G16H 20/00 (2018.01); G06T 2207/10064 (2013.01); G06T 2207/20036 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The present disclosure relates generally to an autonomous cell imaging and modeling platform, and more specifically to machine-learning techniques for using microscopy imaging data to continuously study live biological cells. The autonomous cell imaging and modeling platform can be applied to evaluate various cellular processes, such as cellular differentiation, optimization of cell culture (e.g., in-plate cytometry), disease modeling, histopathology imaging, and genetic and chemical screening, using a dynamic universal imaging system. In some embodiments, the platform comprises a set of label-free computational imaging techniques, self-supervised learning models, and robotic devices configured in an autonomous imaging system to study positional and morphological characteristics in particular cellular substructures of a cell culture in an efficient and non-destructive manner over time.


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