The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Dec. 08, 2022
Applicant:

Life Technologies Corporation, Carlsbad, CA (US);

Inventors:

John Nobile, Guilford, CT (US);

George Thomas Roth, Fairfield, CT (US);

Todd Rearick, Cheshire, CT (US);

Jonathan Schultz, Oxford, MA (US);

Jonathan M. Rothberg, Guilford, CT (US);

David Marran, Durham, CT (US);

Assignee:

Life Technologies Corporation, Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/30 (2006.01); B01L 3/00 (2006.01); G01N 27/414 (2006.01);
U.S. Cl.
CPC ...
G01N 27/301 (2013.01); B01L 3/502761 (2013.01); G01N 27/4145 (2013.01); B01J 2219/00315 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/005 (2013.01); B01J 2219/00653 (2013.01); B01J 2219/00722 (2013.01); B01L 2200/0668 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0877 (2013.01);
Abstract

An apparatus includes a reaction vessels coupled to an electronic sensor for monitoring a reaction product in the reaction vessel; a fluidics system for sequentially delivering a plurality of reagents to the reaction vessel, the fluidics system including a plurality of reagent reservoirs in fluidic communication via a plurality of flow paths with a fluidics circuit and to a common passage in fluidic communication between the fluidics circuit and the reaction vessel, a solution reservoir in fluidic communication with the common passage via a branch passage connected with the common passage at a junction between the fluidics circuit and the reaction vessel; and an electrode in contact with a solution within the branch passage, the electrode being in electrical communication with the reaction vessel through fluid extending from the branch passage and through the common passage, the electronic sensor generating an output signal depending on a voltage of the electrode.


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