The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Feb. 25, 2019
Applicant:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Inventors:
David Vanhoute, Tarrytown, NY (US);
Steven Davis, Tarrytown, NY (US);
Assignee:
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12N 15/10 (2006.01); C12Q 1/6806 (2018.01); C12Q 1/6809 (2018.01); C12Q 1/6848 (2018.01); C12Q 1/6869 (2018.01); C12Q 1/6888 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/70 (2013.01); C12N 15/1003 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/6809 (2013.01); C12Q 1/6848 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6888 (2013.01); C12Q 2535/122 (2013.01);
Abstract
The present disclosure is directed to a streamlined sample preparation process, VERA (iralnrichment byeducingrtifacts), to tilt total genomic material in favor of DNA/RNA viral genomes. This reduction of host genomic artifacts can be completed in <8 hours from sample acquisition. Using a rapid library preparation protocol (˜1.5 minutes) and real-time nanopore sequencing, potential viral contamination, for example RNA viral contamination, can be identified in less than one workday from sample acquisition.