The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Aug. 20, 2019
Applicants:

The Broad Institute, Inc., Cambridge, MA (US);

The Brigham and Women's Hospital, Inc., Boston, MA (US);

Inventors:

Amit Choudhary, Boston, MA (US);

Kurt Cox, Cambridge, MA (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/44 (2006.01); A61K 31/397 (2006.01); C12N 9/22 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/44 (2013.01); A61K 31/397 (2013.01); C12N 9/22 (2013.01); G01N 2333/922 (2013.01); G01N 2500/00 (2013.01);
Abstract

Compositions and methods are provided for the inhibition of the function of RNA guided endonucleases, including the identification and use of such inhibitors. Methods of identifying inhibitor compounds of RNA guided nucleases, assays for detecting nuclease activity and compounds for use therein are also provided.


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