The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 13, 2020
Applicant:

Biomerieux SA, Marcy l'Etoile, FR;

Inventors:

Jean-Philippe Charrier, Tassin la demi Lune, FR;

Nadine Perrot, Montluel, FR;

Gilles Zambardi, Tignieu Jameyzieu, FR;

Assignee:

BIOMERIEUX, Marcy l'Etoile, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/18 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); G01N 33/6851 (2013.01);
Abstract

A process for determining the sensitivity or resistance of at least one identified bacterium to at least one antibiotic, wherein the process includes the following steps: a) bringing a sample including bacterium into contact with the at least one antibiotic, the antibiotic inducing the rupture of the bacterial wall and/or of the cytoplasmic membrane and causing the release of the intracellular compounds of the bacterium when the bacterium is termed 'sensitive' to the at least one antibiotic, b) incubating the sample with the at least one antibiotic, c) purifying the sample by removing the intact bacteria and the cell debris, d) analyzing the purified sample by mass spectrometry, e) detecting the presence or absence of at least one peak of at least one protein characteristic of the bacterium, and f) determining the sensitivity or the resistance of the bacterial population to the antibiotic.


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