The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Oct. 11, 2024
Applicant:

Invisishield Technologies Ltd., Emeryville, CA (US);

Inventors:

Cheng Liu, Orinda, CA (US);

Hongbing Zhang, Moraga, CA (US);

Ziyou Cui, Seattle, WA (US);

Zhiyuan Yang, Richmond, CA (US);

Jinyun Chen, Emeryville, CA (US);

Jingbao Liu, Castro Valley, CA (US);

Guangyan Xiong, Emeryville, CA (US);

Warner Greene, Hillsborough, CA (US);

Assignee:

INVISISHIELD TECHNOLOGIES LTD., Emeryville, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 31/14 (2006.01); A61K 38/00 (2006.01); C12N 9/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/485 (2013.01); A61P 31/14 (2018.01); C12Y 304/17023 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present application relates to compositions for preventing or treating infections. In some embodiments, the present application provides chimeric proteins comprising a target-binding moiety comprising an extracellular binding domain (EBD) of an angiotensin-converting enzyme 2 (ACE2) protein or a fragment thereof that specifically binds to an S protein, and a positively charged mucoadhesive peptide fragment. Compositions comprising the chimeric proteins described herein are useful for preventing or treating a viral infection in an individual, such as a coronavirus infection.


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