The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2025
Filed:
Jan. 25, 2023
Applicant:
University of Vermont and State Agriculture College, Burlington, VT (US);
Inventor:
Jeffrey Spees, Burlington, VT (US);
Assignee:
University of Vermont and State Agricultural College, Burlington, VT (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); A61K 35/34 (2015.01); A61P 9/04 (2006.01); A61P 9/10 (2006.01); C12N 5/071 (2010.01); C12N 5/074 (2010.01); C12N 5/077 (2010.01); C12N 5/0775 (2010.01); A61K 38/18 (2006.01); A61K 38/28 (2006.01); A61K 38/30 (2006.01); C07K 14/475 (2006.01); C07K 14/62 (2006.01); C07K 14/65 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); A61K 35/34 (2013.01); A61P 9/04 (2018.01); A61P 9/10 (2018.01); C12N 5/0663 (2013.01); C12N 5/0692 (2013.01); C12N 5/0696 (2013.01); A61K 38/18 (2013.01); A61K 38/28 (2013.01); A61K 38/30 (2013.01); C07K 14/475 (2013.01); C07K 14/62 (2013.01); C07K 14/65 (2013.01);
Abstract
The invention features compositions featuring (a) one or more of connective tissue growth factor (CTGF) and human C-terminal CTGF peptide; and (b) one or more of insulin and IGF-1; and methods of using such compositions to reduce cardiac tissue damage associated with an ischemic event or to enhance engraftment of a cell in a cardiac tissue.