The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Dec. 03, 2019
Applicant:

University Health Network, Toronto, CA;

Inventors:

Michael Alan Laflamme, Toronto, CA;

Wahiba Dhahri, Toronto, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/077 (2010.01); C12N 5/0735 (2010.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0657 (2013.01); C12N 5/0606 (2013.01); C12N 5/0607 (2013.01); C12N 2500/25 (2013.01); C12N 2501/115 (2013.01); C12N 2501/155 (2013.01); C12N 2501/16 (2013.01); C12N 2501/165 (2013.01); C12N 2501/33 (2013.01); C12N 2501/415 (2013.01); C12N 2506/02 (2013.01); C12N 2506/03 (2013.01);
Abstract

Provided herein are methods for large-scale in vitro maturation of cardiomyocytes derived from human pluripotent stem cells, compositions prepared by these methods, and use of these compositions in cardiac regeneration.


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