The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2025

Filed:

Nov. 08, 2019
Applicant:

Gammadelta Therapeutics Limited, London, GB;

Inventors:

Shristi Bhandari, London, GB;

Samuel Florence, London, GB;

Andrew Hutton, London, GB;

Louisa Mathias, London, GB;

Oliver Nussbaumer, London, GB;

Kalle Soderstrom, London, GB;

Mark Uden, London, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 35/17 (2025.01); C12M 1/04 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0638 (2013.01); A61K 35/17 (2013.01); C12N 5/0646 (2013.01); C12N 2500/90 (2013.01); C12N 2501/2302 (2013.01); C12N 2501/2315 (2013.01);
Abstract

The present invention relates to a method for the isolation of lymphocytes (in particular γδ T cells) from a non-haematopoietic tissue sample comprising the steps of culturing a non-haematopoietic tissue sample which is an intact biopsy obtained from a non-haematopoietic tissue in the presence of Interleukin-2 (IL-2) and Interleukin-15 (IL-15); and collecting a population of lymphocytes cultured from the non-haematopoietic tissue sample. Methods of subsequent expansion are provided, as well as populations of isolated cells obtained by the method and uses thereof.


Find Patent Forward Citations

Loading…